Study on serum lipoproteins variation in smokers and non-smokers of Hyderabad.
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Abstract
Objective: The study was conducted at territory of Hyderabad during 2004. 25 smokers and 25 non-smokers of
20-40 years of age were interviewed and were clinically evaluated before taking blood samples. The smokers
were requested to come in fast for 14 hours except plain water. Their blood sample was collected from anterior
cubital vein. After centrifugation, the serum was separated for paper electrophorectic analysis for lipoprotein
bands. Results revealed average HDL, LDL, VLDL, Triglycerides and total cholesterol in the blood of smokers
were 31.5-38.5, 126-134, 31.5-34.5, 175-225 and 260-280 respectively mg/dl and in non-smokers were 39.0-
43.0, 105-115, 22-28, 69-140 and 140-200 mg/dl respectively. There was significant (p<0.001) difference in lipoproteins were observed among smokers and non-smokers. It was concluded that the reciprocal variation was
seen in circulating lipoproteins. The level of HDL decreased while LDL and VLDL increased along with Triglycerides and total cholesterol.
Keywords: Serum lipoproteins. Atherosclerosis Coronary heart diseases, Lipoprotein-Electrophoresis.
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