COOLING THERAPY FOR NEWBORNS WITH DIAGNOSIS OF MODERATE TO SEVERE HYPOXIC–ISCHEMIC ENCEPHALOPATHY.
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Abstract
Lack of oxygen to neonatal brain because of perinatal
asphyxia can lead to Hypoxic Ischaemic Encephalopathy (HIE) that can manifest as mild, moderate or severe
forms(Severity ranging from hyperactivity to seizures or
coma after birth) This remains an important cause of
Neuro developmental deficit in childhood.
Infants with moderate encephalopathy have a 10 percent risk of death, and those who survive have a 30 percent risk of disabilities.
Sixty percent of infants with severe encephalopathy die,
and many, if not all, survivors are handicapped.
Treatment is currently limited to supportive intensive
care.
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